On September 5, 2025, at a meeting of the one-time specialized academic council PhD9941 at the Kyiv National University of Technologies and Design (KNUTD), the defense of the dissertation of Roman SMISHKO for the degree of Doctor of Philosophy in the field of knowledge 22 Health in the specialty 226 Pharmacy and industrial pharmacy was held. The dissertation on the topic "Development of a pharmaceutical composition with controlled release of antihistamine active pharmaceutical ingredients" was completed under the scientific supervision of Doctor of Pharmaceutical Sciences, Professor, Head of the Department of Industrial Pharmacy Vladyslav STRASHNYI.
The professional review and evaluation of the dissertation work was provided by a one-time specialized academic council consisting of the following members:
chairman – Viktoriia PLAVAN, Doctor of Technical Sciences, Professor, Head of the Department of Chemical Technologies and Resource Saving of KNUTD;
reviewer – Olena ROIK, Candidate of Pharmaceutical Sciences, Associate Professor, Associate Professor of the Department of Industrial Pharmacy of KNUTD;
opponents – Bohdan BURLAKA, Doctor of Pharmaceutical Sciences, Associate Professor, Professor of the Department of Drug Technology of Zaporizhzhia State Medical and Pharmaceutical University; Oleksandr KUKHTENKO, Doctor of Pharmaceutical Sciences, Professor, Professor of the Department of Industrial Technology of Drugs and Cosmetics of the National Pharmaceutical University and Nataliia STADNYTSKA, Candidate of Chemical Sciences, Associate Professor, Associate Professor of the Department of Technology of Biologically Active Compounds, Pharmacy and Biotechnology of the Lviv Polytechnic National University.
The dissertation work of Roman SMISHKO, which is dedicated to the development of a pharmaceutical composition with controlled release of antihistamine active pharmaceutical ingredients, is scientifically sound, timely and fully meets the modern needs of pharmaceutical science and practice, because allergic diseases are one of the leading medical and social problems of modern healthcare. According to estimates by the World Health Organization, approximately a third of humanity suffers from various forms of allergies, which causes a significant burden on the healthcare system worldwide. Therefore, the pharmaceutical composition developed by the graduate student as part of the dissertation research based on the biodegradable polymer carrier poly-D,L-lactide-co-glycolide (PLGA) in the form of a gel, which, when injected subcutaneously, forms an in situ implant and provides controlled and prolonged release of desloratadine, is extremely important and promising. The use of the results of this work in the production practice of pharmaceutical companies will open the possibility of creating new antiallergic drugs of prolonged action, the use of which will contribute to reducing the frequency of taking medications and reducing the risk of adverse reactions. This, in turn, will increase the safety of treatment and significantly improve the quality of life of patients with seasonal and chronic allergic diseases.
Members of the one-time specialized academic council noted the high level of training of the postgraduate student, scientific novelty and practical significance of the results obtained. Based on the voting results, the specialized academic council PhD9941 unanimously decided to award Roman SMISHKO the scientific degree of Doctor of Philosophy in the field of knowledge 22 Health in the specialty 226 Pharmacy and industrial pharmacy.
The staff of the Department of Industrial Pharmacy sincerely congratulates Roman and his scientific supervisor Vladyslav STRASHNYI. We wish him continued progress, new ideas, interesting research projects, and fruitful work that will contribute to strengthening the positions of Ukrainian pharmaceutical science in the international arena.
13.09.2025
